Michal Jedrusiak

Michal Jedrusiak

I am a Medical Student currently enrolled at the University of Krakow (Poland, EU). I am due to earn a Medical Doctor Degree in December 2022. In my last year of medical school, I applied to the Fulbright BioLab Program, a prestigious initiative that awards competitive scholarships to medical students to experience biomedical sciences research in laboratories. In July 2021, I was incredibly fortunate to be selected to work in the laboratory of Dr. Lunardi in the Anesthesiology Department at the University of Virginia. Currently, I am working on two major research projects. The first one is focused on the validation of an animal model of postoperative delirium that combines anesthesia, surgery, and Intensive Care environment to recapitulate the realism of the clinical setting in aged mice. With this aim, I am working on investigating EEG signatures of mice with delirium-like behaviors by analyzing sleep-wake activity and EEG oscillatory dynamics. The second project I am working on is focused on investigating the mechanisms underpinning Rapid Eye Movement sleep rebound following anesthesia with sevoflurane and propofol, two commonly used anesthetics. For this work, I learned how to perform endotracheal intubation and mechanical ventilation in mice, and how to titrate levels of anesthesia to EEG endpoints of delta waves. After medical school, I would like to start an anesthesiology residency program.

3:50 pm - 5:05 pm
Grand 3

Oral Abstracts 3

Moderator: John Newman, MD, PhD, Buck Institute for Research on Aging and UCSF, CA
• Surgery, Anesthesia and Intensive Care Environment Induces Delirium-Like Disruption of Sleep, Circadian Rhythm and EEG Oscillatory Dynamics in Aged Mice
Michal Jedrusiak, University of Virginia Health System, VA
• Relationship Among Biomarkers of Inflammation, Astrocyte Activation and Neuronal Injury and Delirium Duration and Mortality
Peter Conrad,MD, Indiana University School of Medicine, IN
• Delirium Precipitating Factors and Inflammatory Biomarkers in Acutely Ill Older Adults
Thiago J. Avelino-Silva, MD, PhD, Division of Geriatrics, University of Soa Paulo Medical School
• Pre-hospital Prescribing of ACE-Inhibitors and Angiotension Receptor Blockers Does Not Reduce the Incidence of Delirium in Critically Ill Patients
Malissa Mulkey, PhD, Indiana University, IN
• Protective Factors Influence Resilience to Delirium After Elective Orthopaedic Surgery
Emily Bowman, BSc, Queen’s University, Belfast