Igor Feinstein

Igor Feinstein

MD, PhD

I am currently a clinical assistant professor in the Division of Cardiothoracic Anesthesiology within the Department of Anesthesiology, Perioperative and Pain Medicine at Stanford University School of Medicine. I completed the Medical Scientist Training Program at the State University of New York at Stony Brook where my research focused on mental illness using rodent models. In particular, I studied mechanisms that underlay sex differences in a model of schizophrenia. After earning my MD and PhD, I went on to complete a residency in anesthesiology and a fellowship in cardiothoracic anesthesiology at Stanford University. During my clinical training, I became interested in factors that affect mental health in patients undergoing major surgery. A critical aspect of mental health is intact cognition, which are often impaired as a result of surgery. Increasing evidence suggests that cognitive dysfunction after surgery may have a biological link to the processes underlying chronic neurodegenerative disease such as Alzheimer’s Disease. My current research focuses on studying the biological underpinnings of post operative cognitive dysfunction and their relationship to AD using blood-based biomarkers, large scale plasma proteomics and novel methods of immune profiling, together with longitudinal cognitive assessments. The goal of my work is to 1) accurately identify patients at high risk for post-operative cognitive dysfunction, and 2) develop mechanism-based interventions that will improve brain health.

10:20 am - 11:20 am
Grand 3

Oral Abstracts: Session 1

• An Immune Signature of Postoperative Cognitive Dysfunction (POCD) and its Possible Relevance to Alzheimer’s Disease Neuropathology
Igor Feinstein MD,PhD Stanford University, CA
• The SANDMAN Study: Sleep Apnea, Neuroinflammation, and Cognitive Dysfunction Manifesting After Non-cognitive Surgery
Michael Devinney MD, PhD, Duke University, NC
• Association of Blood Brain Barrier Biomarkers with Delirium in Hip Fracture Population
Natalie Wang , Johns Hopkins University, MD
• Investigation of Serum Biomarkers Associated with In-patient Status and Postoperative Delirium Following Major Cardiac Surgery
Tina McKay MD, PhD, Mass General Hospital, MA