
Mfon Umoh MD PhD recently published a study entitled, "Frequent in dementia, deadliest without it: delirium and mortality in hospitalised older adults (Age and Ageing)." The study was co-authored by fellow ADS members Dr. Thiago J Avelino-Silva , Dr. Marlon Juliano Romero Aliberti, and Dr. Esther Oh.
About the study:
Delirium is common in hospitalized older adults and linked to increased mortality, but it is unclear whether this risk differs by patients’ baseline cognitive status. Using data from the multicenter international study cohort, CHANGE (Creating a Hospital Assessment Network in Geriatrics), that included 2556 adults ≥65 years across 43 hospitals, we examined the association between delirium and 90-day mortality and tested whether baseline dementia modified that relationship. Although delirium occurred more often in patients with dementia, its relative association with 90-day mortality was strongest in those without preexisting dementia. These findings support conducting intervention trials to see whether delirium prevention and management can reduce mortality, especially among patients without known dementia.
Dr. Umoh is affiliated with Johns Hopkins University School of Medicine Division of Geriatric Medicine and Gerontology ; Sarah Miller Coulson Next Generation, Center for Innovative Medicine (CIM) Human Aging Project (HAP) Scholar .
View the article here