
Dr. Niccolo Terrando, PhD recently published a study entitled "Electrical stimulation of the vagus nerve improves amyloid pathology in delirium superimposed on dementia," in the Bioelectronic Medicine journal.
This study establishes a novel role for neuromodulation using minimally invasive percutaneous vagus nerve stimulation (pVNS) to regulate postoperative immunity, including interleukin-6, microglial activation, and deposition of amyloid-beta in the brain of Alzheimer's disease-like mice. This work advances a new paradigm for perioperative interventions in patients at risk for delirium superimposed on dementia.
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